THE SCIENCE BEHIND DOGVIAR
Because we love dogs just like you do.
Relevance of proteins enriched in Caviar Oil to pet’s health.
Several of the proteins enriched in sturgeon roe sack (placenta) have potentially beneficial
functions to pets’ health.
A recent study analyzed a set of ageing-related genetic variants in dogs (single nucleotide
polymorphisms, SNPs), and found a marginally significant association between one SNP and
longevity residuals that were corrected for body weight in pedigree dog breeds in the original
analysis, and also in the majority of resampled data sets. This SNP lies in a novel dog gene
(ENSCAFG00000002337) that is a homolog to the human peroxiredoxin 1 (PRDX1) gene. This gene
does not appear to be regularly discussed in relation to body weight, but has previously been
demonstrated to be important for protection against apoptosis and oxidative stress, and the
promotion of longevity in a range of organisms (Lee 2003; Olahova et al. 2008; Radyuk et al. 2009;
Nystrom et al. 2012; De Haes et al. 2014).
Superoxide dismutase (SOD) and gluthatione peroxidase (GPx) as antioxidants
Oxidative stress is recognized a key factor in several diseases in companion animals, especially
linked to aging. Oxidative stress increases with age and can also be influences by factors including
diet, lifestyle, physical injury or environmental conditions like pollution, noise and crowds. Two
proteins enriched in caviar oil (SOD and GPx) are essential anti-oxidants and may be beneficial to
counteract progressive oxidative stress.
Feeding an antioxidant blend of vitamins, minerals and carotenoids to a mixed adult dog
population resulted in increased total antioxidant activity, significant reductions in both
endogenous and exogenous DNA damage and higher vaccine-specific virus-neutralizing antibody
levels following rabies vaccination. Antioxidant supplements were also shown to significantly
reduce DNA damage in cats with renal insufficiency, that have a tendency to oxidative stress.
Another common age-related condition in dogs is the decline of visual function, including retinal
degeneration and cloudy lens (nuclear sclerosis).
Antioxidant supplementation has shown potential long-term benefits for the preservation and
improvement of various functions of the canine eye.
Oxidative stress may also be involved in the cognitive decline that is associated with advanced age.
Antioxidant diet in aged canines resulted in a significant improvement in the ability of aged but
not young animals to acquire progressively more difficult learning tasks. Recent laboratory
studies indicate that aged cats show impairments on cognitive tasks similar to those used in dogs.
Finally, the antioxidant role of SOD and GPx were investigated in a few studies looking at dog
semen cryopreservation (which has drawn a striking attraction since artificial insemination (AI) has
been introduced as a powerful tool to manage dog breeding programs).
The studies found that
supplementing the semen samples with SOD plus GPx improved the sperm quality of both chilled
and frozen‐thawed semen, particularly sperm viability and DNA integrity.
Full paper available here